Cathepsin W, T-cell receptor-associated transmembrane adapter 1, lymphotactin and killer cell lectin like receptor K1 are sensitive and specific RNA biomarkers of canine epitheliotropic lymphoma

Cutaneous T-cell lymphoma (CTCL) is an uncommon type of lymphoma involving malignant skin-resident or skin-homing T cells.Canine epitheliotropic lymphoma (EL) is the most common form of CTCL in dogs, and it also spontaneously arises from T lymphocytes in the mucosa and skin.Clinically, it can be difficult to distinguish early-stage CTCLs apart from

read more

Revisiting enduring values

The paper discusses the Foulard e teli copri-allattamento nature of values in general and the nature and utility of the values of librarianship.Delineates the changes that have occurred and are occurring in the wider world and the nature of change; also the importance of values in providing a framework for dealing with present and future change.Str

read more

Programmatic implications of implementing the relational algebraic capacitated location (RACL) algorithm outcomes on the allocation of laboratory sites, test volumes, platform distribution and space requirements

Introduction: CD4 testing in South Africa is based on an integrated tiered service delivery model that matches testing demand with capacity.The National Health Laboratory Service has predominantly implemented laboratory-based CD4 Outdoor Play Equipment testing.Coverage gaps, over-/under-capacitation and optimal placement of point-of-care (POC) test

read more


Computational evaluation and benchmark study of 342 crystallographic holo-structures of SARS-CoV-2 Mpro enzyme

Abstract The coronavirus disease 19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to a global health crisis with millions of confirmed cases and related deaths.The main protease (Mpro) of SARS-CoV-2 is crucial for viral replication and presents an attractive target for drug development.Despite the approva

read more